|
|
L-lactate <=> D-lactate
|
5.1.2.1
lactate racemase
5.1.2.2
mandelate racemase
|
–
–
|
BK
|
|
BRENDA:
BR178
KEGG:
R01450
MetaCyc:
LACTATE-RACEMASE-RXN
|
|
|
|
D-lactate + NAD+ <=> pyruvate + NADH + H+
|
1.1.1.27
L-lactate dehydrogenase
1.1.1.28
D-lactate dehydrogenase
1.1.1.345
D-2-hydroxyacid dehydrogenase (NAD+)
|
–
–
–
|
BMK
|
|
BRENDA:
BR29291
KEGG:
R00704
MetaCyc:
DLACTDEHYDROGNAD-RXN
SABIO-RK:
155
|
|
|
|
D-lactate + acceptor <=> pyruvate + reduced_acceptor
|
1.1.99.6
D-lactate dehydrogenase (acceptor)
|
–
|
K
|
|
BRENDA:
BR29379
KEGG:
R00297
MetaCyc:
D-2-HYDROXY-ACID-DEHYDROGENASE-RXN
SABIO-RK:
791
|
|
|
|
D-lactate + ferricytochrome_b5 <=> pyruvate + ferricytochrome_b5 + H+
|
1.1.2.5
D-lactate dehydrogenase (cytochrome c-553)
|
–
|
K
|
|
BRENDA:
BR36727
KEGG:
R00198
MetaCyc:
1.1.2.5-RXN
|
|
|
|
D-alanine + D-lactate + ATP <=> D-alanyl-(R)-lactate + ADP + phosphate
|
6.1.2.1
D-alanine---(R)-lactate ligase
6.3.2.4
D-alanine---D-alanine ligase
|
–
–
|
M
|
|
BRENDA:
BR49562
KEGG:
R09588
MetaCyc:
RXN-11298
SABIO-RK:
9613
|
|
|
|
D-lactate + H+ <=> methylglyoxal + H2O
|
3.5.1.124
protein deglycase
4.2.1.130
D-lactate dehydratase
|
–
–
|
BK
|
|
BRENDA:
BR49777
KEGG:
R09796
MetaCyc:
GLYOXIII-RXN
|
|
|
|
N-acetylmuramate_6-phosphate + H2O <=> N-acetyl-D-glucosamine_6-phosphate + D-lactate
|
4.2.1.126
N-acetylmuramic acid 6-phosphate etherase
|
–
|
MK
|
|
BRENDA:
BR49999
KEGG:
R08555
MetaCyc:
RXN0-4641
|
|
|
|
an_S-(1-hydroxy-2-oxopropyl)-[protein]-L-cysteine + H2O <=> protein + D-lactate + H+
|
3.5.1.124
protein deglycase
|
–
|
|
|
BRENDA:
BR51902
MetaCyc:
RXN-17634
|
|
|
|
(R)-2-hydroxyglutarate + pyruvate <=> 2-oxoglutarate + D-lactate
|
1.1.99.40
(R)-2-hydroxyglutarate---pyruvate transhydrogenase
|
–
|
K
|
|
BRENDA:
BR51923
KEGG:
R11593
MetaCyc:
RXN-18432
|
|
|
|
D-Lactaldehyde + NAD+ + H2O <=> H+ + D-lactate + NADH
|
1.2.1.22
lactaldehyde dehydrogenase
1.2.1.23
2-oxoaldehyde dehydrogenase (NAD+)
1.2.1.3
aldehyde dehydrogenase (NAD+)
|
–
–
–
|
MK
|
|
BRENDA:
BS189164
KEGG:
R01735
MetaCyc:
LACTALDEHYDE-OXI-RXN
SABIO-RK:
548
|
|
|
|
propionyl-CoA + D-lactate <=> propionate + (R)-lactoyl-CoA
|
2.8.3.1
propionate CoA-transferase
|
–
|
BM
|
|
BRENDA:
BS360569
MetaCyc:
LACCOA-RXN
|
|
|
|
L-2-chloropropionate + H2O <=> D-lactate + Cl- + H+
|
3.8.1.10
2-haloacid dehalogenase (configuration-inverting)
3.8.1.2
(S)-2-haloacid dehalogenase
|
–
–
|
M
|
|
BRENDA:
BS363226
MetaCyc:
RXN-15138
|
|
|
|
S-D-lactoylglutathione + H2O <=> H+ + glutathione + D-lactate
|
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
|
BMK
|
|
BRENDA:
BS364477
KEGG:
R01736
MetaCyc:
GLYOXII-RXN
SABIO-RK:
283
|
|
|
|
ubiquinone + D-lactate <=> ubiquinol + pyruvate
|
1.1.5.10
D-2-hydroxyacid dehydrogenase (quinone)
1.1.5.12
D-lactate dehydrogenase (quinone)
|
–
–
|
M
|
|
BRENDA:
BS426223
MetaCyc:
DLACTDEHYDROGFAD-RXN
|
|
|
|
D-lactate + 2 ferricytochrome_c <=> pyruvate + 2 ferricytochrome_c + 2 H+
|
1.1.2.4
D-lactate dehydrogenase (cytochrome)
|
–
|
BK
|
|
BRENDA:
BR36726
KEGG:
R00197
|
|
|
|
D-Lactate_2-sulfate + H2O <=> D-lactate + sulfate
|
3.1.6.17
D-lactate-2-sulfatase
|
–
|
|
|
BRENDA:
BR48172
KEGG:
R01448
|
|
|
|
D-lactate + a_quinone <=> pyruvate + a_quinol
|
1.1.5.12
D-lactate dehydrogenase (quinone)
|
–
|
K
|
|
BRENDA:
BR51921
KEGG:
R11591
|
|
|
|
mono-(lactoyl)trypanothione + H2O <=> trypanothione + D-lactate
|
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
|
|
|
BRENDA:
BS364478
SABIO-RK:
10533
|
|
|
|
bis-(lactoyl)trypanothione + H2O <=> trypanothione + D-lactate
|
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
|
|
|
BRENDA:
BS364479
SABIO-RK:
10517
|
|
|
|
S-Lactoylglutathione + H2O <=> D-lactate + glutathione
|
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
|
|
|
BRENDA:
BS382777
SABIO-RK:
10510
|
|
|
|
D-lactate + phenazine_methosulfate <=> pyruvate + reduced_phenazine_methosulfate
|
1.1.5.12
D-lactate dehydrogenase (quinone)
1.1.99.6
D-lactate dehydrogenase (acceptor)
|
–
–
|
|
|
BRENDA:
BS438558
SABIO-RK:
14551
|
|
|
|
D-lactate + oxidized_c-type_cytochrome <=> pyruvate + ferricytochrome_c + H+
|
1.1.2.4
D-lactate dehydrogenase (cytochrome)
|
–
|
M
|
|
MetaCyc:
D-LACTATE-DEHYDROGENASE-CYTOCHROME-RXN
|
|
|
|
acetyl-CoA + D-lactate <=> acetate + (R)-lactoyl-CoA
|
2.8.3.1
propionate CoA-transferase
|
–
|
M
|
|
MetaCyc:
RXN-15723
|
|
|
|
D-lactate + NAD+ + reduced_ferredoxin_[iron-sulfur]_cluster <=> pyruvate + NADH + oxidized_ferredoxin
|
1.3.1.110
lactate dehydrogenase (NAD+,ferredoxin)
|
–
|
|
|
MetaCyc:
RXN-16836
|
|
|
|
an_Nomega-(1-hydroxy-2-oxopropyl)-[protein]-L-arginine + H2O <=> filaggrin_L-Arg + D-lactate + H+
|
3.5.1.124
protein deglycase
|
–
|
|
|
MetaCyc:
RXN-17630
|
|
|
|
an_N6-(1-hydroxy-2-oxopropyl)-[protein]-L-lysine + H2O <=> a_[protein]-L-tyrosine + D-lactate
|
3.5.1.124
protein deglycase
|
–
|
|
|
MetaCyc:
RXN-17632
|
|
|
|
electron-transfer_quinone + D-lactate <=> electron-transfer_quinol + pyruvate
|
1.1.5.12
D-lactate dehydrogenase (quinone)
|
–
|
M
|
|
MetaCyc:
RXN-20917
|
|
|
|
pyruvate + H+ + e- <=> D-lactate
|
not assigned
|
–
|
|
|
MetaCyc:
RXN0-5261
|
|
|
|
D-lactate + H+ <=> D-lactate + H+
|
not assigned
|
–
|
|
|
MetaCyc:
TRANS-RXN0-515
|
|
|
|
(S)-2-chloropropionate + H2O <=> D-lactate + Cl-
|
3.8.1.2
(S)-2-haloacid dehalogenase
|
–
|
|
|
BRENDA:
BS454764
|
|
|
|
D-lactate + O2 <=> pyruvate + H2O2
|
1.1.3.15
(S)-2-hydroxy-acid oxidase
|
–
|
|
|
BRENDA:
BS257489
|
|
|
|
D-lactate + 2,6-dichlorophenolindophenol <=> pyruvate + reduced_2,6-dichlorophenolindophenol
|
1.1.2.4
D-lactate dehydrogenase (cytochrome)
1.1.5.10
D-2-hydroxyacid dehydrogenase (quinone)
1.1.5.12
D-lactate dehydrogenase (quinone)
|
–
–
–
|
|
|
BRENDA:
BS388454
|
|
|
|
D-lactate + ferricyanide <=> pyruvate + ferrocyanide
|
1.1.2.4
D-lactate dehydrogenase (cytochrome)
1.1.2.5
D-lactate dehydrogenase (cytochrome c-553)
1.1.5.12
D-lactate dehydrogenase (quinone)
1.1.99.6
D-lactate dehydrogenase (acceptor)
|
–
–
–
–
|
|
|
BRENDA:
BS257358
|
|
|
|
(R)-lactamide + H2O <=> D-lactate + NH3
|
3.5.1.4
amidase
3.5.1.86
mandelamide amidase
|
–
–
|
|
|
BRENDA:
BS396893
|
|
|
|
(S)-2-bromopropionic_acid + H2O <=> D-lactate + Br-
|
3.8.1.10
2-haloacid dehalogenase (configuration-inverting)
3.8.1.2
(S)-2-haloacid dehalogenase
|
–
–
|
|
|
BRENDA:
BS419224
|
|
|
|
D-lactate + Oxidized_benzyl_viologen <=> pyruvate + reduced_benzyl_viologen
|
1.1.99.30
2-oxo-acid reductase
|
–
|
|
|
BRENDA:
BS372932
|
|
|
|
S-(1-hydroxy-2-oxopropyl)-N-acetyl-L-cysteine + H2O <=> N-acetyl-L-cysteine + D-lactate
|
3.5.1.124
protein deglycase
|
–
|
|
|
BRENDA:
BS439874
|
|
|
|
D-lactate + carbamoyl_methyl_viologen <=> pyruvate + reduced_carboxamido-methyl_viologen
|
1.1.99.30
2-oxo-acid reductase
|
–
|
|
|
BRENDA:
BS372933
|
|
|
|
D-lactate + oxidized_1,1''-carbamoyl_methyl_viologen <=> pyruvate + reduced_1,1''-carbamoyl_methyl_viologen
|
1.1.99.30
2-oxo-acid reductase
|
–
|
|
|
BRENDA:
BS372930
|
|
|
|
D-lactate + 2 Ferrocytochrome <=> pyruvate + 2 Ferrocytochrome
|
1.1.2.4
D-lactate dehydrogenase (cytochrome)
|
–
|
|
|
BRENDA:
BS409156
|
|
|
|
D-lactate + oxidized_anthraquinone-2,6-disulfonate <=> pyruvate + reduced_anthraquinone-2,6-disulfonate
|
1.1.99.30
2-oxo-acid reductase
|
–
|
|
|
BRENDA:
BS371392
|
|
|
|
D-lactate + oxidized_phenazine_methosulfate <=> pyruvate + reduced_phenazine_methosulfate
|
1.1.2.4
D-lactate dehydrogenase (cytochrome)
1.1.5.12
D-lactate dehydrogenase (quinone)
|
–
–
|
|
|
BRENDA:
BS438559
|
|
|
|
D-lactate + 2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-2H-tetrazolium_bromide <=> pyruvate + reduced_3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium_bromide
|
1.1.99.6
D-lactate dehydrogenase (acceptor)
|
–
|
|
|
BRENDA:
BS422222
|
|
|
|
D-lactate + cytochrome_c2ox <=> pyruvate + cytochrome_c2red
|
1.1.1.28
D-lactate dehydrogenase
1.1.2.4
D-lactate dehydrogenase (cytochrome)
|
–
–
|
|
|
BRENDA:
BS372928
|
|
|
|
D-lactate + oxidized_2,6-dichlorophenolindophenol <=> pyruvate + reduced_2,6-dichlorophenolindophenol
|
1.1.5.10
D-2-hydroxyacid dehydrogenase (quinone)
1.1.99.6
D-lactate dehydrogenase (acceptor)
|
–
–
|
|
|
BRENDA:
BS422220
|
|
|
|
Nomega-(1-hydroxy-2-oxopropyl)-Nalpha-acetyl-L-arginine + H2O <=> acetyl-L-Arg + D-lactate
|
3.5.1.124
protein deglycase
|
–
|
|
|
BRENDA:
BS439873
|
|
|
|
D-lactate + reduced_thiazolyl_blue <=> pyruvate + reduced_3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl_tetrazolium
|
1.1.5.12
D-lactate dehydrogenase (quinone)
1.1.99.6
D-lactate dehydrogenase (acceptor)
|
–
–
|
|
|
BRENDA:
BS422221
|
|
|
|
N6-(1-hydroxy-2-oxopropyl)-N2-acetyl-L-lysine + H2O <=> N-alpha-acetyl-L-lysine + D-lactate
|
3.5.1.124
protein deglycase
|
–
|
|
|
BRENDA:
BS439875
|
|
|
|
Nalpha,Nepsilon-diacetyl-L-Lys-D-Ala-D-lactate + H2O <=> Nalpha,Nepsilon-diacetyl-L-Lys-D-Ala + D-lactate
|
3.4.16.4
serine-type D-Ala-D-Ala carboxypeptidase
|
–
|
|
|
BRENDA:
BS36675
|
|
|
|
an_S-(1-hydroxy-2-oxopropyl)-[aspartate_aminotransferase]-L-arginine + H2O <=> a_[aspartate_aminotransferase]-L-arginine + D-lactate
|
3.5.1.124
protein deglycase
|
–
|
|
|
BRENDA:
BS439119
|
|
|
|
an_S-(1-hydroxy-2-oxopropyl)-[aspartate_aminotransferase]-L-lysine + H2O <=> a_[aspartate_aminotransferase]-L-lysine + D-lactate
|
3.5.1.124
protein deglycase
|
–
|
|
|
BRENDA:
BS439120
|
|
|
|
an_S-(1-hydroxy-2-oxopropyl)-[bovine_serum_albumin]-L-amino_acid + H2O <=> a_[bovine_serum_albumin]-L-amino_acid + D-lactate
|
3.5.1.124
protein deglycase
|
–
|
|
|
BRENDA:
BS439121
|
|
|
|
an_S-(1-hydroxy-2-oxopropyl)-[bovine_serum_albumin]-L-lysine + H2O <=> a_[bovine_serum_albumin]-L-lysine + D-lactate
|
3.5.1.124
protein deglycase
|
–
|
|
|
BRENDA:
BS439122
|
|
|
|
an_S-(1-hydroxy-2-oxopropyl)-[fructose-1,6-biphosphate_aldolase]-L-arginine + H2O <=> a_[fructose-1,6-biphosphate_aldolase]-L-arginine + D-lactate
|
3.5.1.124
protein deglycase
|
–
|
|
|
BRENDA:
BS439123
|
|
|
|
an_S-(1-hydroxy-2-oxopropyl)-[fructose-1,6-biphosphate_aldolase]-L-lysine + H2O <=> a_[fructose-1,6-biphosphate_aldolase]-L-lysine + D-lactate
|
3.5.1.124
protein deglycase
|
–
|
|
|
BRENDA:
BS439124
|
|
|
|
an_S-(1-hydroxy-2-oxopropyl)-[glyceraldehyde-3-phosphate_dehydrogenase]-L-cysteine + H2O <=> a_[glyceraldehyde-3-phosphate_dehydrogenase]-L-cysteine + D-lactate
|
3.5.1.124
protein deglycase
|
–
|
|
|
BRENDA:
BS439125
|
|
|
|
an_S-(1-hydroxy-2-oxopropyl)-[protein]-L-arginine + H2O <=> [myelin_basic_protein]-arginine + D-lactate
|
3.5.1.124
protein deglycase
|
–
|
|
|
BRENDA:
BS438189
|
|
|
|
an_S-(1-hydroxy-2-oxopropyl)-[protein]-L-lysine + H2O <=> a_[protein]-L-lysine + D-lactate
|
3.5.1.124
protein deglycase
|
–
|
|
|
BRENDA:
BS438191
|
|
|
|
an_S-(1-hydroxy-2-oxopropyl)-[protein]-N-acetyl-L-arginine + H2O <=> [myelin_basic_protein]-arginine + D-lactate
|
3.5.1.124
protein deglycase
|
–
|
|
|
BRENDA:
BS439126
|
|
|
|
an_S-(1-hydroxy-2-oxopropyl)-[protein]-N-acetyl-L-cysteine + H2O <=> a_[protein]-L-cysteine + D-lactate
|
3.5.1.124
protein deglycase
|
–
|
|
|
BRENDA:
BS439127
|
|
|
|
an_S-(1-hydroxy-2-oxopropyl)-[protein]-N-acetyl-L-lysine + H2O <=> a_[protein]-L-lysine + D-lactate
|
3.5.1.124
protein deglycase
|
–
|
|
|
BRENDA:
BS439128
|
|
|
|
S-(1-hydroxy-2-oxopropyl)-[bovine_serum_albumin]-N-acetyl-L-cysteine + H2O <=> [bovine_serum_albumin]-L-cysteine + D-lactate
|
3.5.1.124
protein deglycase
|
–
|
|
|
BRENDA:
BS439876
|
|
|
|
S-D-lactoyltrypanothione + 2 H2O <=> 2 D-lactate + trypanothione
|
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
|
|
|
BRENDA:
BS399013
|
|
|
|
D-alanine + D-lactate + ATP <=> D-Ala-D-lactate + ADP + phosphate
|
6.1.2.1
D-alanine---(R)-lactate ligase
6.3.2.4
D-alanine---D-alanine ligase
|
–
–
|
|
|
BRENDA:
BS411924
|
|
|
|
DL-2-chloropropionate + H2O <=> D-lactate + Cl-
|
3.8.1.2
(S)-2-haloacid dehalogenase
|
–
|
|
|
BRENDA:
BS363251
|
|
|
|
D-malate <=> D-lactate + CO2
|
4.1.1.101
malolactic enzyme
|
–
|
|
|
BRENDA:
BS433613
|
|
|
|
D-lactoyltrypanothione + H2O <=> D-lactate + trypanothione
|
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
|
|
|
BRENDA:
BS391756
|
|
|
|
deamino-NADH + H+ + pyruvate <=> D-lactate + deamido-NAD+
|
1.1.1.28
D-lactate dehydrogenase
|
–
|
|
|
SABIO-RK:
10882
|
|